U.S. Department of Health and Human Services — National Institutes of Health

tumor suppressor

Discover > tumor suppressor

3DPX-014604

Crystal structure of a hydroxylated HIF-1...
Roman Fischer

Protein-peptide complex, tumor suppressor, cancer, proteosomal degradation, ubiquitin, prolyl hydroxylation, GENE REGULATION

3DPX-014243

Human p53 core domain with hot spot mutation...
PTB1

Metal-binding, LOOP-SHEET-HELIX MOTIF, TRANSCRIPTION, activator, ANTI-ONCOGENE, Apoptosis, CELL CYCLE, Disease mutation, RESCUE MUTATION, tumor suppressor

3DPX-011351

Crystal structure of a protein phosphatase...
davis797

Protein phosphorylation, Phosphatase, PP2A, B56, tumor suppressor, Methylation, HYDROLASE, TOXIN, HYDROLASE-HYDROLASE INHIBITOR complex

3DPX-009324

Crystal structure of the p53 core domain...
rcc9427

p53 core domain, PROTEIN-DNA INTERACTION, self assembled tetramer, activator, Apoptosis, CELL CYCLE, Disease mutation, DNA-binding, endoplasmic reticulum, glycoprotein

3DPX-004439 Tumor Suppressor p53 complexed with DNA

Si Cave's picture

p53, tumor suppressor, DNA

3DPX-003717

Lysine 120-acetylated P53 DNA binding domain...

James Tyrwhitt Drake's picture

James Tyrwhitt Drake

Acetylation, transcription factor, post-translational modification, tumor suppressor, DNA binding specificity, Apoptosis, INDUCED FIT, Genetic code expansion, TRANSCRIPTION

3DPX-002803

Structure of a HIF-1a-pVHL-ElonginB-ElonginC...

nevitdilmen's picture

regulation, tumor suppressor, oxygen sensing, TRANSCRIPTION