U.S. Department of Health and Human Services — National Institutes of Health

NUCLEUS

Discover > NUCLEUS

3DPX-015017

Structure of PLK1 in complex with BI2536
Christopher Hastings

Structure of PLK1, selectivity residues, KINASE, polo-like kinase, structure based drug design, ATP-binding, Nucleotide-binding, NUCLEUS, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE

3DPX-014707

Intact PPAR gamma - RXR alpha Nuclear...
liqiang2

DNA-binding, Host-virus interaction, Metal-binding, NUCLEUS, receptor, TRANSCRIPTION, TRANSCRIPTION REGULATION, Zinc-finger, activator, Diabetes mellitus

3DPX-014203

Crystal structure of serum and...
anajafov

AGC PROTEIN KINASE, Apoptosis, ATP-binding, endoplasmic reticulum, Nucleotide-binding, NUCLEUS, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, KINASE

3DPX-011644

Human NR4A1 ligand-binding domain
LimingPei

NUCLEAR RECEPTOR, Structural Genomics, Structural Genomics Consortium, SGC, DNA-binding, Metal-binding, NUCLEUS, PHOSPHORYLATION, TRANSCRIPTION, TRANSCRIPTION REGULATION

3DPX-011642

humanRXR alpha & mouse LXR alpha...
LimingPei

Nuclear hormone receptor nonsteroidal LXR agonist choloestorol metabolism, DNA-binding, Host-virus interaction, Metal-binding, NUCLEUS, Polymorphism, receptor, TRANSCRIPTION, TRANSCRIPTION REGULATION, Ubl conjugation

3DPX-011566

Crystal structure of human YAP and TEAD...
terdiv4

immunoglobulin-like fold, activator, Disease mutation, DNA-binding, NUCLEUS, Phosphoprotein, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSCRIPTION-PROTEIN BINDING complex

3DPX-011474

Crystal structure of the R482W mutant of...
roshna_r

Immunoglobulin fold, lamin, Cardiomyopathy, Charcot-Marie-Tooth disease, Disease mutation, Intermediate filament, Limb-girdle muscular dystrophy, Lipoprotein, NUCLEUS, Phosphoprotein

3DPX-010859

Wild Type HIV-1 Protease with potent...
TAN WOON YAN

HIV-1, wild type protease, Protease inhibitor, HYDROLASE, AIDS, Aspartyl protease, capsid maturation, Capsid protein, Cytoplasm, DNA INTEGRATION