Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor Pyrazolo-pyrimidinone 5

Autogenerated by

for

dlkerr

Created on Thu, 2020-09-17 18:11, last updated on Thu, 2020-09-17 18:11

I Printed This

Remix It

Vertical Tabs

General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-014847

Category

Proteins, Macromolecules and Viruses

Keyword(s)

SHP2, PTPN11, Protein tyrosine phosphatase, Phosphatase, allosteric inhibitor, HYDROLASE-HYDROLASE INHIBITOR complex, HYDROLASE

Protein Data Bank ID

6MDB

Experimental Method

X-RAY DIFFRACTION

Resolution

2.34

Model Details

Associated Species

Escherichia coli

Oligomeric Details

monomeric

Scattering Type

x-ray

Attribution

PubMed ID

30 688 459

Digital Object Identifier (DOI)

10.1021/acs.jmedchem.8b01726

Citation Title

6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors.

Citation Year

2019

STL/VRML Files

PDB-6MDB-ribbon-secondary.wrl

PDB-6MDB-ribbon-rainbow.wrl

PDB-6MDB-ribbon-bychain.wrl

PDB-6MDB-ribbon.stl

PDB-6MDB-surf-bychain.wrl

PDB-6MDB-surf-hydropathy.wrl

PDB-6MDB-surf-coulombic.wrl

PDB-6MDB-surf.stl

PDB-6MDB.zip

X3D Files

PDB-6MDB-ribbon-secondary.x3d

PDB-6MDB-ribbon-rainbow.x3d

PDB-6MDB-ribbon-bychain.x3d

PDB-6MDB-ribbon.x3d

PDB-6MDB-surf-bychain.x3d

PDB-6MDB-surf-hydropathy.x3d

PDB-6MDB-surf-coulombic.x3d

PDB-6MDB-surf.x3d

QR Code for https://3dprint.nih.gov/discover/3dpx-014847

Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor Pyrazolo-pyrimidinone 5

I Printed This

Remix It

Vertical Tabs

STL/VRML Files

X3D Files

Rating

Licensing

Comments

0