U.S. Department of Health and Human Services — National Institutes of Health

Crystal Structure of Murine Cereblon in Complex with Thalidomide

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Duncan.Brownsey

Created on Tue, 2020-07-21 00:40, last updated on Tue, 2020-07-21 00:40

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-014690

Category

Proteins, Macromolecules and Viruses

Keyword(s)

ubiquitin ligase, DCAF, LIGASE

Protein Data Bank ID

Experimental Method

X-RAY DIFFRACTION

Resolution

1.880

Model Details

Associated Species

Escherichia coli

Oligomeric Details

monomeric

R-Factor

0.17520

Scattering Type

x-ray

Attribution

Citation Title

Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex

STL/VRML Files

PDB-4TZC-ribbon-secondary.wrl

PDB-4TZC-ribbon-rainbow.wrl

PDB-4TZC-ribbon-bychain.wrl

PDB-4TZC-ribbon.stl

PDB-4TZC-surf-bychain.wrl

PDB-4TZC-surf-hydropathy.wrl

PDB-4TZC-surf-coulombic.wrl

PDB-4TZC-surf.stl

X3D Files

PDB-4TZC-ribbon-secondary.x3d

PDB-4TZC-ribbon-rainbow.x3d

PDB-4TZC-ribbon-bychain.x3d

PDB-4TZC-ribbon.x3d

PDB-4TZC-surf-bychain.x3d

PDB-4TZC-surf-hydropathy.x3d

PDB-4TZC-surf-coulombic.x3d

PDB-4TZC-surf.x3d

PDB-4TZC-ribbon-secondary.x3d

PDB-4TZC-ribbon-rainbow.x3d

PDB-4TZC-ribbon-bychain.x3d

PDB-4TZC-ribbon.x3d

PDB-4TZC-surf-bychain.x3d

PDB-4TZC-surf-hydropathy.x3d

PDB-4TZC-surf-coulombic.x3d

PDB-4TZC-surf.x3d

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