U.S. Department of Health and Human Services — National Institutes of Health

Crystal Structure of human KRAS G12C covalently bound to AMG 510

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Created on Mon, 2020-05-11 22:16, last updated on Mon, 2020-05-11 22:16

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-014301

Category

Proteins, Macromolecules and Viruses

Keyword(s)

INHIBITOR, GTPase, SIGNALING PROTEIN

Protein Data Bank ID

Experimental Method

X-RAY DIFFRACTION

Resolution

1.65

Model Details

Associated Species

Escherichia coli

Oligomeric Details

monomeric

R-Factor

0.18252

Scattering Type

x-ray

Attribution

PubMed ID

Digital Object Identifier (DOI)

10.1038/s41586-019-1694-1

Citation Title

The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity.

Citation Year

2019

STL/VRML Files

PDB-6OIM-ribbon-secondary.wrl

PDB-6OIM-ribbon-rainbow.wrl

PDB-6OIM-ribbon-bychain.wrl

PDB-6OIM-ribbon.stl

PDB-6OIM-surf-bychain.wrl

PDB-6OIM-surf-hydropathy.wrl

PDB-6OIM-surf-coulombic.wrl

PDB-6OIM-surf.stl

X3D Files

PDB-6OIM-ribbon-secondary.x3d

PDB-6OIM-ribbon-rainbow.x3d

PDB-6OIM-ribbon-bychain.x3d

PDB-6OIM-ribbon.x3d

PDB-6OIM-surf-bychain.x3d

PDB-6OIM-surf-hydropathy.x3d

PDB-6OIM-surf-coulombic.x3d

PDB-6OIM-surf.x3d

PDB-6OIM-ribbon-secondary.x3d

PDB-6OIM-ribbon-rainbow.x3d

PDB-6OIM-ribbon-bychain.x3d

PDB-6OIM-ribbon.x3d

PDB-6OIM-surf-bychain.x3d

PDB-6OIM-surf-hydropathy.x3d

PDB-6OIM-surf-coulombic.x3d

PDB-6OIM-surf.x3d

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