Crystal Structure of Aurora2 kinase in complex with a GSK3beta inhibitor

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linuszwaka

Created on Wed, 2020-04-22 21:11, last updated on Wed, 2020-04-22 21:11

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-013987

Category

Proteins, Macromolecules and Viruses

Keyword(s)

Kinase inhibitor complex, ATP-binding, CELL CYCLE, Cytoplasm, cytoskeleton, KINASE, Nucleotide-binding, Phosphoprotein, Polymorphism, SERINE/THREONINE-PROTEIN KINASE

Protein Data Bank ID

3LAU

Experimental Method

X-RAY DIFFRACTION

Resolution

2.1

Model Details

Associated Species

Escherichia coli

Oligomeric Details

monomeric

Scattering Type

x-ray

Attribution

PubMed ID

20 167 481

Digital Object Identifier (DOI)

10.1016/j.bmcl.2010.01.114

Citation Title

Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2.

Citation Year

2010

STL/VRML Files

PDB-3LAU-ribbon-secondary.wrl

PDB-3LAU-ribbon-rainbow.wrl

PDB-3LAU-ribbon-bychain.wrl

PDB-3LAU-ribbon.stl

PDB-3LAU-surf-bychain.wrl

PDB-3LAU-surf-hydropathy.wrl

PDB-3LAU-surf-coulombic.wrl

PDB-3LAU-surf.stl

PDB-3LAU.zip

X3D Files

PDB-3LAU-ribbon-secondary.x3d

PDB-3LAU-ribbon-rainbow.x3d

PDB-3LAU-ribbon-bychain.x3d

PDB-3LAU-ribbon.x3d

PDB-3LAU-surf-bychain.x3d

PDB-3LAU-surf-hydropathy.x3d

PDB-3LAU-surf-coulombic.x3d

PDB-3LAU-surf.x3d

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Crystal Structure of Aurora2 kinase in complex with a GSK3beta inhibitor

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