THE X-RAY STRUCTURE OF A COMPLEX OF SIALIC ACID AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

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Created on Sun, 2020-02-09 20:53, last updated on Sun, 2020-02-09 20:53

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-012945

Category

Proteins, Macromolecules and Viruses

Keyword(s)

neuraminidase, INFLUENZA PROTEIN, DRUG RESISTANT VARIANT, sialic acid, SECOND BINDING SITE, GLYCOSYLATED PROTEIN, HYDROLASE

Protein Data Bank ID

2QWB

Experimental Method

X-RAY DIFFRACTION

Resolution

1.8

Model Details

Oligomeric Details

tetrameric

R-Factor

0.166

Scattering Type

x-ray

Attribution

PubMed ID

9 655 825

Digital Object Identifier (DOI)

10.1016/S0969-2126(98)00075-6

Citation Title

Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase.

Citation Year

1998

STL/VRML Files

PDB-2QWB-ribbon-secondary.wrl

PDB-2QWB-ribbon-rainbow.wrl

PDB-2QWB-ribbon-bychain.wrl

PDB-2QWB-ribbon.stl

PDB-2QWB-surf-bychain.wrl

PDB-2QWB-surf-hydropathy.wrl

PDB-2QWB-surf-coulombic.wrl

PDB-2QWB-surf.stl

PDB-2QWB.zip

X3D Files

PDB-2QWB-ribbon-secondary.x3d

PDB-2QWB-ribbon-rainbow.x3d

PDB-2QWB-ribbon-bychain.x3d

PDB-2QWB-ribbon.x3d

PDB-2QWB-surf-bychain.x3d

PDB-2QWB-surf-hydropathy.x3d

PDB-2QWB-surf-coulombic.x3d

PDB-2QWB-surf.x3d

QR Code for https://3dprint.nih.gov/discover/3dpx-012945

THE X-RAY STRUCTURE OF A COMPLEX OF SIALIC ACID AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

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