U.S. Department of Health and Human Services — National Institutes of Health

Mouse cyclic GMP-AMP synthase (cGAS) in complex with DNA

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Created on Wed, 2019-08-21 19:41, last updated on Wed, 2019-08-21 19:41

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-011782

Category

Proteins, Macromolecules and Viruses

Protein Data Bank ID

Keyword(s)

Immune response

TRANSFERASE-DNA complex

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

Escherichia coli

Resolution

1.86

Oligomeric Details

hexameric

R-Factor

0.1871

Scattering Type

x-ray

Attribution

PubMed ID

Digital Object Identifier (DOI)

10.1016/j.celrep.2014.01.003

The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.

Citation Year

2014

STL/VRML Files

PDB-4O6A-ribbon-secondary.wrl

PDB-4O6A-ribbon-rainbow.wrl

PDB-4O6A-ribbon-bychain.wrl

PDB-4O6A-ribbon.stl

PDB-4O6A-surf-bychain.wrl

PDB-4O6A-surf-hydropathy.wrl

PDB-4O6A-surf-coulombic.wrl

PDB-4O6A-surf.stl

X3D Files

PDB-4O6A-ribbon-secondary.x3d

PDB-4O6A-ribbon-rainbow.x3d

PDB-4O6A-ribbon-bychain.x3d

PDB-4O6A-ribbon.x3d

PDB-4O6A-surf-bychain.x3d

PDB-4O6A-surf-hydropathy.x3d

PDB-4O6A-surf-coulombic.x3d

PDB-4O6A-surf.x3d

PDB-4O6A-ribbon-secondary.x3d

PDB-4O6A-ribbon-rainbow.x3d

PDB-4O6A-ribbon-bychain.x3d

PDB-4O6A-ribbon.x3d

PDB-4O6A-surf-bychain.x3d

PDB-4O6A-surf-hydropathy.x3d

PDB-4O6A-surf-coulombic.x3d

PDB-4O6A-surf.x3d

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