Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator

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pjkritsch

Created on Mon, 2018-12-10 16:05, last updated on Mon, 2018-12-10 16:06

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-010248

Category

Proteins, Macromolecules and Viruses

Keyword(s)

GCASE, HYDROLASE, glycoprotein, GLYCOSIDASE, GLUCOSYLCERAMIDASE, PROT, PROTEROS BIOSTRUCTURES GMBH

Protein Data Bank ID

5LVX

Experimental Method

X-RAY DIFFRACTION

Resolution

2.20

Model Details

Associated Species

Homo sapiens

Oligomeric Details

tetrameric

R-Factor

0.18907

Scattering Type

x-ray

Attribution

PubMed ID

29 676 907

Digital Object Identifier (DOI)

10.1021/jacs.7b13003

Citation Title

beta-Glucocerebrosidase Modulators Promote Dimerization of beta-Glucocerebrosidase and Reveal an Allosteric Binding Site.

Citation Year

2018

STL/VRML Files

PDB-5LVX-ribbon-secondary.wrl

PDB-5LVX-ribbon-rainbow.wrl

PDB-5LVX-ribbon-bychain.wrl

PDB-5LVX-ribbon.stl

PDB-5LVX-surf-bychain.wrl

PDB-5LVX-surf-hydropathy.wrl

PDB-5LVX-surf-coulombic.wrl

PDB-5LVX-surf.stl

PDB-5LVX.zip

X3D Files

PDB-5LVX-ribbon-secondary.x3d

PDB-5LVX-ribbon-rainbow.x3d

PDB-5LVX-ribbon-bychain.x3d

PDB-5LVX-ribbon.x3d

PDB-5LVX-surf-bychain.x3d

PDB-5LVX-surf-hydropathy.x3d

PDB-5LVX-surf-coulombic.x3d

PDB-5LVX-surf.x3d

QR Code for https://3dprint.nih.gov/discover/3dpx-010248

Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator

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