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Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator
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pjkritsch
Created on Mon, 2018-12-10 16:05, last updated on Mon, 2018-12-10 16:06
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General Information
This Model was autogenerated from the
"Quick Submit"
tool.
Model ID
3DPX-010248
Category
Proteins, Macromolecules and Viruses
Keyword(s)
GCASE, HYDROLASE, glycoprotein, GLYCOSIDASE, GLUCOSYLCERAMIDASE, PROT, PROTEROS BIOSTRUCTURES GMBH
Protein Data Bank ID
5LVX
Experimental Method
X-RAY DIFFRACTION
Resolution
2.20
Model Details
Associated Species
Homo sapiens
Oligomeric Details
tetrameric
R-Factor
0.18907
Scattering Type
x-ray
Attribution
PubMed ID
29 676 907
Digital Object Identifier (DOI)
10.1021/jacs.7b13003
Citation Title
beta-Glucocerebrosidase Modulators Promote Dimerization of beta-Glucocerebrosidase and Reveal an Allosteric Binding Site.
Citation Year
2018
STL/VRML Files
PDB-5LVX-ribbon-secondary.wrl
PDB-5LVX-ribbon-rainbow.wrl
PDB-5LVX-ribbon-bychain.wrl
PDB-5LVX-ribbon.stl
PDB-5LVX-surf-bychain.wrl
PDB-5LVX-surf-hydropathy.wrl
PDB-5LVX-surf-coulombic.wrl
PDB-5LVX-surf.stl
PDB-5LVX.zip
X3D Files
PDB-5LVX-ribbon-secondary.x3d
PDB-5LVX-ribbon-rainbow.x3d
PDB-5LVX-ribbon-bychain.x3d
PDB-5LVX-ribbon.x3d
PDB-5LVX-surf-bychain.x3d
PDB-5LVX-surf-hydropathy.x3d
PDB-5LVX-surf-coulombic.x3d
PDB-5LVX-surf.x3d
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