LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid(Compound N41)

Autogenerated by for

Meghan McCarthy

Created on Thu, 2018-03-29 17:19, last updated on Thu, 2018-03-29 17:19

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID 

3DPX-008946

Category 

Proteins, Macromolecules and Viruses

Keyword(s) 

DEMETHYLASE INHIBITION, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex, OXIDOREDUCTASE, OXIDOREDUCTASE-INHIBITOR complex

Protein Data Bank ID 

6BGW

Experimental Method 

X-RAY DIFFRACTION

Resolution 

1.64

Model Details

Associated Species 

Escherichia coli

Oligomeric Details 

monomeric

R-Factor 

0.1895

Scattering Type 

x-ray

Attribution

PubMed ID 

29 537 847

Digital Object Identifier (DOI) 

10.1021/acs.jmedchem.8b00261

Citation Title 

Insights into the action of inhibitor enantiomers against histone lysine demethylase 5A.

Citation Year 

2018

STL/VRML Files

 

PDB-6BGW-ribbon-secondary.wrl

PDB-6BGW-ribbon-rainbow.wrl

PDB-6BGW-ribbon-bychain.wrl

PDB-6BGW-ribbon.stl

PDB-6BGW-surf-bychain.wrl

PDB-6BGW-surf-hydropathy.wrl

PDB-6BGW-surf-coulombic.wrl

PDB-6BGW-surf.stl

PDB-6BGW.zip

X3D Files

 

PDB-6BGW-ribbon-secondary.x3d

PDB-6BGW-ribbon-rainbow.x3d

PDB-6BGW-ribbon-bychain.x3d

PDB-6BGW-ribbon.x3d

PDB-6BGW-surf-bychain.x3d

PDB-6BGW-surf-hydropathy.x3d

PDB-6BGW-surf-coulombic.x3d

PDB-6BGW-surf.x3d

Rating

Select ratingGive LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid(Compound N41) 1/5Give LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid(Compound N41) 2/5Give LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid(Compound N41) 3/5Give LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid(Compound N41) 4/5Give LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid(Compound N41) 5/5Cancel rating

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