U.S. Department of Health and Human Services — National Institutes of Health

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

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Created on Wed, 2017-03-29 05:51, last updated on Wed, 2017-03-29 05:51

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-004706

Category

Proteins, Macromolecules and Viruses

Protein Data Bank ID

Keyword(s)

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

Escherichia coli

Resolution

1.85

Oligomeric Details

monomeric

R-Factor

0.17211

Scattering Type

x-ray

Attribution

PubMed ID

22 431 598

Digital Object Identifier (DOI)

10.1073/pnas.1116510109

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.

Citation Year

2012

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

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