U.S. Department of Health and Human Services — National Institutes of Health

Crystal structure of HIV-1 reverse transcriptase (RT) in complex with Rilpivirine (TMC278, Edurant), a non-nucleoside rt-inhibiting drug

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Created on Thu, 2017-03-23 20:25, last updated on Thu, 2017-03-23 20:26

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-004685

Category

Proteins, Macromolecules and Viruses

Protein Data Bank ID

Keyword(s)

NONNUCLEOSIDE INHIBITOR

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

Escherichia coli

Resolution

1.5

Oligomeric Details

dimeric

R-Factor

0.1550

Scattering Type

x-ray

Attribution

PubMed ID

23 422 558

Digital Object Identifier (DOI)

10.1038/nchem.1559

Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase.

Citation Year

2013

Crystal structure of HIV-1 reverse transcriptase (RT) in complex with Rilpivirine (TMC278, Edurant), a non-nucleoside rt-inhibiting drug

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