U.S. Department of Health and Human Services — National Institutes of Health

Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-2-naphthonitrile (JLJ649), a Non-nucleoside Inhibitor

Autogenerated by

for

tinchunchu

Created on Thu, 2017-03-16 20:27, last updated on Thu, 2022-12-08 14:36

Vertical Tabs

General Information

Model ID

3DPX-004666

Category

Proteins, Macromolecules and Viruses

Keyword(s)

polymerase, Reverse Transcriptase, HIV, NON-NUCLEOSIDE INHIBITOR, TRANSFERASE, HYDROLASE-DNA-INHIBITOR complex, HYDROLASE-INHIBITOR complex

Protein Data Bank ID

5TEP

This entry is obsolete and was removed from the distribution of released PDB entries, and has been superseded by PDB ID 5X47. It is no longer a Quick Submit but has been retained for archival purposes.

Experimental Method

X-RAY DIFFRACTION

Resolution

3.0990

Model Details

Associated Species

Escherichia coli BL21(DE3)

Oligomeric Details

dimeric

R-Factor

0.2278

Scattering Type

x-ray

Attribution

PubMed ID

27 994 756

Digital Object Identifier (DOI)

10.1021/acsmedchemlett.6b00390

Citation Title

Design, Conformation, and Crystallography of 2-Naphthyl Phenyl Ethers as Potent Anti-HIV Agents.

Citation Year

2016

Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-2-naphthonitrile (JLJ649), a Non-nucleoside Inhibitor

I Printed This

Remix It

Vertical Tabs

STL/VRML Files

X3D Files

Blender Files

Rating

Licensing

Comments

0