U.S. Department of Health and Human Services — National Institutes of Health

Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP

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James Tyrwhitt Drake

Created on Fri, 2017-01-06 13:53, last updated on Fri, 2017-01-06 13:53

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-004390

Category

Proteins, Macromolecules and Viruses

Keyword(s)

ALPHA-BETA-ALPHA SANDWICH, HYDROLASE, DNA damage, DNA repair, DNA replication

Protein Data Bank ID

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

Escherichia coli BL21(DE3)

Resolution

1.21

Oligomeric Details

monomeric

R-Factor

0.1377

Scattering Type

x-ray

Attribution

Structural and kinetic study on the different substrate recognition mechanism of human MTH1 for 8-oxo-dGTP and 2-oxo-dATP: New mechanism for broad substrate specificity of enzymes

STL/VRML Files

PDB-5GHI-ribbon-secondary.wrl

PDB-5GHI-ribbon-rainbow.wrl

PDB-5GHI-ribbon-bychain.wrl

PDB-5GHI-ribbon.stl

PDB-5GHI-surf-bychain.wrl

PDB-5GHI-surf-hydropathy.wrl

PDB-5GHI-surf-coulombic.wrl

PDB-5GHI-surf.stl

X3D Files

PDB-5GHI-ribbon-secondary.x3d

PDB-5GHI-ribbon-rainbow.x3d

PDB-5GHI-ribbon-bychain.x3d

PDB-5GHI-ribbon.x3d

PDB-5GHI-surf-bychain.x3d

PDB-5GHI-surf-hydropathy.x3d

PDB-5GHI-surf-coulombic.x3d

PDB-5GHI-surf.x3d

Blender Files

PDB-5GHI-ribbon-secondary.blend

PDB-5GHI-ribbon-rainbow.blend

PDB-5GHI-ribbon-bychain.blend

PDB-5GHI-ribbon.blend

PDB-5GHI-surf-bychain.blend

PDB-5GHI-surf-hydropathy.blend

PDB-5GHI-surf-coulombic.blend

PDB-5GHI-surf.blend

PDB-5GHI-ribbon-secondary.x3d

PDB-5GHI-ribbon-rainbow.x3d

PDB-5GHI-ribbon-bychain.x3d

PDB-5GHI-ribbon.x3d

PDB-5GHI-surf-bychain.x3d

PDB-5GHI-surf-hydropathy.x3d

PDB-5GHI-surf-coulombic.x3d

PDB-5GHI-surf.x3d

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