Crystal structure of a dimer complex of the human glucocorticoid receptor ligand-binding domain bound to dexamethasone and a TIF2 coactivator motif

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Created on Thu, 2016-12-01 18:44, last updated on Thu, 2016-12-01 18:45

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID 

3DPX-004256

Category 

Proteins, Macromolecules and Viruses

Keyword(s) 

glucocorticoid receptor, dexamethasone, TIF2, dimer interface, Hormone binding pocket, charge clamp, Coactivator, HORMONE-HORMONE ACTIVATOR COMPLEX

Protein Data Bank ID 

1M2Z

Experimental Method 

X-RAY DIFFRACTION

Resolution 

2.5

Model Details

Associated Species 

Escherichia coli BL21(DE3)

Oligomeric Details 

tetrameric

R-Factor 

0.267

Scattering Type 

x-ray

Attribution

PubMed ID 

12 151 000

Digital Object Identifier (DOI) 

10.1016/S0092-8674(02)00817-6

Citation Title 

Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

Citation Year 

2002

STL/VRML Files

 

PDB-1M2Z-ribbon-secondary.wrl

PDB-1M2Z-ribbon-rainbow.wrl

PDB-1M2Z-ribbon-bychain.wrl

PDB-1M2Z-ribbon.stl

PDB-1M2Z-surf-bychain.wrl

PDB-1M2Z-surf-hydropathy.wrl

PDB-1M2Z-surf-coulombic.wrl

PDB-1M2Z-surf.stl

PDB-1M2Z.zip

X3D Files

 

PDB-1M2Z-ribbon-secondary.x3d

PDB-1M2Z-ribbon-rainbow.x3d

PDB-1M2Z-ribbon-bychain.x3d

PDB-1M2Z-ribbon.x3d

PDB-1M2Z-surf-bychain.x3d

PDB-1M2Z-surf-hydropathy.x3d

PDB-1M2Z-surf-coulombic.x3d

PDB-1M2Z-surf.x3d

Blender Files

 

PDB-1M2Z-ribbon-secondary.blend

PDB-1M2Z-ribbon-rainbow.blend

PDB-1M2Z-ribbon-bychain.blend

PDB-1M2Z-ribbon.blend

PDB-1M2Z-surf-bychain.blend

PDB-1M2Z-surf-hydropathy.blend

PDB-1M2Z-surf-coulombic.blend

PDB-1M2Z-surf.blend

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