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THREE DIMENSIONAL STRUCTURE OF THE ANTI-ALZHEIMER DRUG, E2020 (ARICEPT), COMPLEXED WITH ITS TARGET ACETYLCHOLINESTERASE
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mpuiatti
Created on Tue, 2016-03-01 09:36, last updated on Tue, 2016-03-01 09:36
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General Information
This Model was autogenerated from the
"Quick Submit"
tool.
Model ID
3DPX-002937
Category
Proteins, Macromolecules and Viruses
Keyword(s)
Alzheimer's disease, drug, SERINE HYDROLASE, ALPHA/BETA HYDROLASE, NEUROTRANSMITTER CLEAVAGE, CATALYTIC TRIAD, GLYCOSYLATED PROTEIN
Protein Data Bank ID
1EVE
Experimental Method
X-RAY DIFFRACTION
Resolution
2.5
Model Details
Oligomeric Details
monomeric
R-Factor
0.188
Scattering Type
x-ray
Attribution
PubMed ID
10 368 299
Digital Object Identifier (DOI)
10.1016/S0969-2126(99)80040-9
Citation Title
Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs.
Citation Year
1999
STL/VRML Files
PDB-1EVE-ribbon-secondary.wrl
PDB-1EVE-ribbon-rainbow.wrl
PDB-1EVE-ribbon-bychain.wrl
PDB-1EVE-ribbon.stl
PDB-1EVE-ribbon-thick.stl
PDB-1EVE-surf-bychain.wrl
PDB-1EVE-surf-hydropathy.wrl
PDB-1EVE-surf-coulombic.wrl
PDB-1EVE-surf.stl
PDB-1EVE.zip
X3D Files
PDB-1EVE-ribbon-secondary.x3d
PDB-1EVE-ribbon-rainbow.x3d
PDB-1EVE-ribbon-bychain.x3d
PDB-1EVE-ribbon.x3d
PDB-1EVE-ribbon-thick.x3d
PDB-1EVE-surf-bychain.x3d
PDB-1EVE-surf-hydropathy.x3d
PDB-1EVE-surf-coulombic.x3d
PDB-1EVE-surf.x3d
Blender Files
PDB-1EVE-ribbon-secondary.blend
PDB-1EVE-ribbon-rainbow.blend
PDB-1EVE-ribbon-bychain.blend
PDB-1EVE-ribbon.blend
PDB-1EVE-ribbon-thick.blend
PDB-1EVE-surf-bychain.blend
PDB-1EVE-surf-hydropathy.blend
PDB-1EVE-surf-coulombic.blend
PDB-1EVE-surf.blend
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