U.S. Department of Health and Human Services — National Institutes of Health

Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the INSTI XZ384 (compound 4a)

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for

James Tyrwhitt Drake

Created on Tue, 2016-02-23 13:46, last updated on Tue, 2016-02-23 13:50

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-002882

Category

Proteins, Macromolecules and Viruses

Keyword(s)

RECOMBINATION, VIRAL PROTEIN/DNA, PROTEIN-DNA COMPLEX, TETRAMER, DNA INTEGRATION, ENDONUCLEASE, Metal-binding, MULTIFUNCTIONAL ENZYME, NUCLEASE, NUCLEOTIDYLTRANSFERASE

Protein Data Bank ID

Experimental Method

X-RAY DIFFRACTION

Resolution

2.58

Model Details

Associated Species

ESCHERICHIA COLI

Oligomeric Details

octameric

R-Factor

0.1858

Scattering Type

x-ray

Attribution

PubMed ID

Digital Object Identifier (DOI)

10.1021/ACSCHEMBIO.5B00948

Citation Title

HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant Mutant Integrases.

Citation Year

2016

STL/VRML Files

PDB-5FRM-ribbon-secondary.wrl

PDB-5FRM-ribbon-rainbow.wrl

PDB-5FRM-ribbon-bychain.wrl

PDB-5FRM-ribbon.stl

PDB-5FRM-ribbon-thick.stl

PDB-5FRM-surf-bychain.wrl

PDB-5FRM-surf-hydropathy.wrl

PDB-5FRM-surf-coulombic.wrl

PDB-5FRM-surf.stl

X3D Files

PDB-5FRM-ribbon-secondary.x3d

PDB-5FRM-ribbon-rainbow.x3d

PDB-5FRM-ribbon-bychain.x3d

PDB-5FRM-ribbon.x3d

PDB-5FRM-ribbon-thick.x3d

PDB-5FRM-surf-bychain.x3d

PDB-5FRM-surf-hydropathy.x3d

PDB-5FRM-surf-coulombic.x3d

PDB-5FRM-surf.x3d

Blender Files

PDB-5FRM-ribbon-secondary.blend

PDB-5FRM-ribbon-rainbow.blend

PDB-5FRM-ribbon-bychain.blend

PDB-5FRM-ribbon.blend

PDB-5FRM-ribbon-thick.blend

PDB-5FRM-surf-bychain.blend

PDB-5FRM-surf-hydropathy.blend

PDB-5FRM-surf-coulombic.blend

PDB-5FRM-surf.blend

PDB-5FRM-ribbon-secondary.x3d

PDB-5FRM-ribbon-rainbow.x3d

PDB-5FRM-ribbon-bychain.x3d

PDB-5FRM-ribbon.x3d

PDB-5FRM-ribbon-thick.x3d

PDB-5FRM-surf-bychain.x3d

PDB-5FRM-surf-hydropathy.x3d

PDB-5FRM-surf-coulombic.x3d

PDB-5FRM-surf.x3d

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