U.S. Department of Health and Human Services — National Institutes of Health

Crystal structure of Cas9 bound to PAM-containing DNA target containing mismatches at positions 1-3

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cruzp2

Created on Tue, 2015-12-22 10:56, last updated on Tue, 2015-12-22 10:56

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-002463

Category

Proteins, Macromolecules and Viruses

Protein Data Bank ID

4UN5

Keyword(s)

HYDROLASE-DNA-RNA COMPLEX

GENOME EDITING

RNP

PROTEIN-RNA COMPLEX

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

ESCHERICHIA COLI

Resolution

2.40

Oligomeric Details

pentameric

R-Factor

0.2165

Scattering Type

x-ray

Attribution

PubMed ID

25 079 318

Digital Object Identifier (DOI)

10.1038/NATURE13579

Structural Basis of Pam-Dependent Target DNA Recognition by the Cas9 Endonuclease

Citation Year

2014

Crystal structure of Cas9 bound to PAM-containing DNA target containing mismatches at positions 1-3

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