U.S. Department of Health and Human Services — National Institutes of Health

Crystal structure of human mitochondrial DNA polymerase holoenzyme

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Created on Fri, 2015-10-16 07:13, last updated on Fri, 2015-10-16 07:13

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-002030

Category

Proteins, Macromolecules and Viruses

Protein Data Bank ID

3IKM

Keyword(s)

Human mitochondrial DNA polymerase

Disease mutation

DNA replication

DNA-binding

DNA-DIRECTED DNA POLYMERASE

Magnesium

Mitochondrion

Neuropathy

NUCLEOTIDYLTRANSFERASE

Progressive external ophthalmoplegia

Model Details

Experimental Method

X-RAY DIFFRACTION

Resolution

3.24

Oligomeric Details

trimeric

R-Factor

0.284

Scattering Type

x-ray

Attribution

PubMed ID

19 837 034

Digital Object Identifier (DOI)

10.1016/j.cell.2009.07.050

Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations.

Citation Year

2009

Crystal structure of human mitochondrial DNA polymerase holoenzyme

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