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Crystal Structure of double mutant Y115E Y117E human Glutaminyl Cyclase in complex with inhibitor PBD-150
Autogenerated by
for
James Tyrwhitt Drake
Created on Fri, 2015-08-07 12:30, last updated on Fri, 2015-08-07 12:31
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General Information
This Model was autogenerated from the
"Quick Submit"
tool.
Model ID
3DPX-001766
Category
Proteins, Macromolecules and Viruses
Keyword(s)
Alzheimer Disease, Cyclotransferase Soluble Variant, PBD-150 inhibitor, TRANSFERASE
Protein Data Bank ID
4YWY
Experimental Method
X-RAY DIFFRACTION
Resolution
1.95
Model Details
Associated Species
Escherichia coli
Oligomeric Details
monomeric
R-Factor
0.16630
Scattering Type
x-ray
Attribution
Digital Object Identifier (DOI)
10.1107/S2053230X15010389
Citation Title
The soluble Y115E-Y117E variant of human glutaminyl cyclase is a valid target for X-ray and NMR screening of inhibitors against Alzheimer disease
Citation Year
2015
STL/VRML Files
PDB-4YWY-ribbon-secondary.wrl
PDB-4YWY-ribbon-rainbow.wrl
PDB-4YWY-ribbon-bychain.wrl
PDB-4YWY-ribbon.stl
PDB-4YWY-ribbon-thick.stl
PDB-4YWY-surf-bychain.wrl
PDB-4YWY-surf-hydropathy.wrl
PDB-4YWY-surf-coulombic.wrl
PDB-4YWY-surf.stl
PDB-4YWY.zip
X3D Files
PDB-4YWY-ribbon-secondary.x3d
PDB-4YWY-ribbon-rainbow.x3d
PDB-4YWY-ribbon-bychain.x3d
PDB-4YWY-ribbon.x3d
PDB-4YWY-ribbon-thick.x3d
PDB-4YWY-surf-bychain.x3d
PDB-4YWY-surf-hydropathy.x3d
PDB-4YWY-surf-coulombic.x3d
PDB-4YWY-surf.x3d
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