U.S. Department of Health and Human Services — National Institutes of Health

Leptin receptor, mAb 9F8 fab heavy/light chains

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Created on Mon, 2015-03-09 23:36, last updated on Tue, 2015-03-10 00:02

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-001171

Category

Proteins, Macromolecules and Viruses

Keyword(s)

Receptor-antibody complex, Cytokine receptor, Antibody Fab fragment, Immunoglobulin fold, Leptin Receptor-antibody complex, IMMUNE SYSTEM

Protein Data Bank ID

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

Escherichia coli

Resolution

1.95

Oligomeric Details

trimeric

R-Factor

0.1735

Scattering Type

x-ray

Attribution

PubMed ID

Digital Object Identifier (DOI)

10.1016/j.str.2012.01.019

Citation Title

Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody.

Citation Year

2012

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3V6O-surf-coulombic.x3d

3V6O-surf.x3d

QR Code for https://3dprint.nih.gov/discover/3dpx-001171

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