U.S. Department of Health and Human Services — National Institutes of Health

Cryo-electron tomography average of an C1-IgG complex

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Created on Sat, 2014-06-14 12:01, last updated on Mon, 2015-05-04 10:19

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-000245

Category

Proteins, Macromolecules and Viruses

Electron Microscopy Data Bank ID

Keyword(s)

C1-immune complex

classical complement activation

Model Details

Experimental Method

Other

Sample

DNP-haptenated liposomes, polyclonal goat anti-DNP Antibody, human C1 (originating from C4 depleted serum)

Resolution

66

Contour Level

Attribution

PubMed ID

Digital Object Identifier (DOI)

10.1126/science.1248943

Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJR, van de Winkel JGJ, Wilson IA, Koster AJ, Taylor RP, Ollmann Saphire E, Burton DR, Schuurman J, Gros P, Parren PWHI

Complement is activated by IgG hexamers assembled at the cell surface.

Citation Year

2014

STL/VRML Files

EMDB-2506-surf.stl

EMDB-2506-surf-radial.wrl

X3D Files

2506-surf-radial.x3d

X3D Files

EMDB-2506-surf-radial.x3d

EMDB-2506-surf.x3d

EMDB-2506-surf-radial.x3d

EMDB-2506-surf.x3d

QR Code for https://3dprint.nih.gov/discover/3dpx-000245

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