U.S. Department of Health and Human Services — National Institutes of Health

3D Structure of Alzheimer's Abeta(1-42) fibrils

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3Dprint@NIH

Fri, 2014-04-25 20:01

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-000028

Category

Proteins, Macromolecules and Viruses

Keyword(s)

Alzheimer's, fibril, protofilament, beta-sandwich, quenched hydrogen/deuterium exchange, pairwise mutagenesis, protein fibril

Protein Data Bank ID

2BEG

Experimental Method

SOLUTION NMR

Sample

Homo sapiens

Model Origin

Molecular data (e.g., crystallography)

Molecular Weight

22.6 kDa

Model Details

Associated Species

Escherichia coli BL21(DE3)

UniProt Reference Number

P05067

Oligomeric Details

pentameric

Scattering Type

x-ray

Attribution

PubMed ID

16 293 696

Digital Object Identifier (DOI)

10.1073/pnas.0506723102

Citation Title

3D structure of Alzheimer's amyloid-{beta}(1-42) fibrils.

Citation Year

2005

3D Structure of Alzheimer's Abeta(1-42) fibrils

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