The PROTAC MZ1 in complex with the second bromodomain of Brd4 and pVHL:ElonginC:ElonginB

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edwinhui94

Created on Fri, 2022-10-21 10:58, last updated on Fri, 2022-10-21 10:58

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-017725

Category

Proteins, Macromolecules and Viruses

Keyword(s)

PROTAC complex, targeted degradation, chromatin reader, ubiquitin ligase, bifunctional ligand, LIGASE

Protein Data Bank ID

5T35

Experimental Method

X-RAY DIFFRACTION

Resolution

2.700

Model Details

Associated Species

Escherichia coli BL21(DE3)

Oligomeric Details

tetrameric

R-Factor

0.2067

Scattering Type

x-ray

Attribution

PubMed ID

28 288 108

Digital Object Identifier (DOI)

10.1038/nchembio.2329

Citation Title

Structural basis of PROTAC cooperative recognition for selective protein degradation.

Journal

Nat. Chem. Biol.

Citation Year

2017

STL/VRML Files

PDB-5T35-ribbon-secondary.wrl

PDB-5T35-ribbon-rainbow.wrl

PDB-5T35-ribbon-bychain.wrl

PDB-5T35-ribbon.stl

PDB-5T35-surf-bychain.wrl

PDB-5T35-surf-hydropathy.wrl

PDB-5T35-surf-coulombic.wrl

PDB-5T35-surf.stl

PDB-5T35.zip

X3D Files

PDB-5T35-ribbon-secondary.x3d

PDB-5T35-ribbon-rainbow.x3d

PDB-5T35-ribbon-bychain.x3d

PDB-5T35-ribbon.x3d

PDB-5T35-surf-bychain.x3d

PDB-5T35-surf-hydropathy.x3d

PDB-5T35-surf-coulombic.x3d

PDB-5T35-surf.x3d

QR Code for https://3dprint.nih.gov/discover/3dpx-017725

The PROTAC MZ1 in complex with the second bromodomain of Brd4 and pVHL:ElonginC:ElonginB

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