U.S. Department of Health and Human Services — National Institutes of Health

Mitogen-activated protein kinase kinase 1 (MEK1) in complex with CH4858061 and MgATP

Autogenerated by

for

Nuclear Juicer

Created on Mon, 2022-06-27 12:35, last updated on Mon, 2022-06-27 13:02

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-017281

Category

Proteins, Macromolecules and Viruses

Keyword(s)

KINASE, kinase inhibitor, allosteric, TRANSFERASE-TRANSFERASE INHIBITOR complex

Protein Data Bank ID

Experimental Method

X-RAY DIFFRACTION

Resolution

2.77

Model Details

Associated Species

Escherichia coli

Oligomeric Details

monomeric

Scattering Type

x-ray

Attribution

PubMed ID

Digital Object Identifier (DOI)

10.1016/j.bmcl.2011.01.062

Citation Title

Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent.

Journal

Bioorg.Med.Chem.Lett.

Citation Year

2011

STL/VRML Files

PDB-3OS3-ribbon-secondary.wrl

PDB-3OS3-ribbon-rainbow.wrl

PDB-3OS3-ribbon-bychain.wrl

PDB-3OS3-ribbon.stl

PDB-3OS3-surf-bychain.wrl

PDB-3OS3-surf-hydropathy.wrl

PDB-3OS3-surf-coulombic.wrl

PDB-3OS3-surf.stl

X3D Files

PDB-3OS3-ribbon-secondary.x3d

PDB-3OS3-ribbon-rainbow.x3d

PDB-3OS3-ribbon-bychain.x3d

PDB-3OS3-ribbon.x3d

PDB-3OS3-surf-bychain.x3d

PDB-3OS3-surf-hydropathy.x3d

PDB-3OS3-surf-coulombic.x3d

PDB-3OS3-surf.x3d

PDB-3OS3-ribbon-secondary.x3d

PDB-3OS3-ribbon-rainbow.x3d

PDB-3OS3-ribbon-bychain.x3d

PDB-3OS3-ribbon.x3d

PDB-3OS3-surf-bychain.x3d

PDB-3OS3-surf-hydropathy.x3d

PDB-3OS3-surf-coulombic.x3d

PDB-3OS3-surf.x3d

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