U.S. Department of Health and Human Services — National Institutes of Health

X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a complex with ligand and MgATP

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Nuclear Juicer

Created on Mon, 2022-06-27 12:30, last updated on Mon, 2022-06-27 12:30

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-017270

Category

Proteins, Macromolecules and Viruses

Keyword(s)

protein kinase structure; Mitogen activated protein kinase kinase; signal transduction; ligand co-complex, ternary co-complex with kinase, ligand and MgATP; non-competitive protein kinase inhibitor, TRANSFERASE

Protein Data Bank ID

Experimental Method

X-RAY DIFFRACTION

Resolution

2.8

Model Details

Associated Species

Escherichia coli

Oligomeric Details

dimeric

Scattering Type

x-ray

Attribution

PubMed ID

Digital Object Identifier (DOI)

10.1021/jm0704548

Citation Title

4-anilino-5-carboxamido-2-pyridone derivatives as noncompetitive inhibitors of mitogen-activated protein kinase kinase.

Journal

J.Med.Chem.

Citation Year

2007

STL/VRML Files

PDB-2P55-ribbon-secondary.wrl

PDB-2P55-ribbon-rainbow.wrl

PDB-2P55-ribbon-bychain.wrl

PDB-2P55-ribbon.stl

PDB-2P55-surf-bychain.wrl

PDB-2P55-surf-hydropathy.wrl

PDB-2P55-surf-coulombic.wrl

PDB-2P55-surf.stl

X3D Files

PDB-2P55-ribbon-secondary.x3d

PDB-2P55-ribbon-rainbow.x3d

PDB-2P55-ribbon-bychain.x3d

PDB-2P55-ribbon.x3d

PDB-2P55-surf-bychain.x3d

PDB-2P55-surf-hydropathy.x3d

PDB-2P55-surf-coulombic.x3d

PDB-2P55-surf.x3d

PDB-2P55-ribbon-secondary.x3d

PDB-2P55-ribbon-rainbow.x3d

PDB-2P55-ribbon-bychain.x3d

PDB-2P55-ribbon.x3d

PDB-2P55-surf-bychain.x3d

PDB-2P55-surf-hydropathy.x3d

PDB-2P55-surf-coulombic.x3d

PDB-2P55-surf.x3d

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