Crystal structure of a interleukin-2 variant in complex with interleukin-2 receptor

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Nimrod1990

Created on Mon, 2022-01-03 01:49, last updated on Mon, 2022-01-03 01:49

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-016615

Category

Proteins, Macromolecules and Viruses

Keyword(s)

Interleukine-2, interleukine-2 receptor, IMMUNE SYSTEM, cytokine, interleukine-2 variant

Protein Data Bank ID

5M5E

Experimental Method

X-RAY DIFFRACTION

Resolution

2.3

Model Details

Associated Species

Homo sapiens

Oligomeric Details

trimeric

R-Factor

0.20053

Scattering Type

x-ray

Attribution

PubMed ID

28 405 498

Digital Object Identifier (DOI)

10.1080/2162402X.2016.1277306

Citation Title

Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines.

Citation Year

2017

STL/VRML Files

PDB-5M5E-ribbon-secondary.wrl

PDB-5M5E-ribbon-rainbow.wrl

PDB-5M5E-ribbon-bychain.wrl

PDB-5M5E-ribbon.stl

PDB-5M5E-surf-bychain.wrl

PDB-5M5E-surf-hydropathy.wrl

PDB-5M5E-surf-coulombic.wrl

PDB-5M5E-surf.stl

PDB-5M5E.zip

X3D Files

PDB-5M5E-ribbon-secondary.x3d

PDB-5M5E-ribbon-rainbow.x3d

PDB-5M5E-ribbon-bychain.x3d

PDB-5M5E-ribbon.x3d

PDB-5M5E-surf-bychain.x3d

PDB-5M5E-surf-hydropathy.x3d

PDB-5M5E-surf-coulombic.x3d

PDB-5M5E-surf.x3d

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Crystal structure of a interleukin-2 variant in complex with interleukin-2 receptor

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