Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors

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Created on Fri, 2021-02-05 16:21, last updated on Fri, 2021-02-05 16:21

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-015463

Category

Proteins, Macromolecules and Viruses

Keyword(s)

PROTEIN KINASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex

Protein Data Bank ID

4R1V

Experimental Method

X-RAY DIFFRACTION

Resolution

1.200

Model Details

Associated Species

Spodoptera frugiperda

Oligomeric Details

monomeric

R-Factor

0.146

Scattering Type

x-ray

Attribution

PubMed ID

25 736 998

Digital Object Identifier (DOI)

10.1016/j.bmcl.2015.02.002

Citation Title

Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors.

Citation Year

2015

STL/VRML Files

PDB-4R1V-ribbon-secondary.wrl

PDB-4R1V-ribbon-rainbow.wrl

PDB-4R1V-ribbon-bychain.wrl

PDB-4R1V-ribbon.stl

PDB-4R1V-surf-bychain.wrl

PDB-4R1V-surf-hydropathy.wrl

PDB-4R1V-surf-coulombic.wrl

PDB-4R1V-surf.stl

PDB-4R1V.zip

X3D Files

PDB-4R1V-ribbon-secondary.x3d

PDB-4R1V-ribbon-rainbow.x3d

PDB-4R1V-ribbon-bychain.x3d

PDB-4R1V-ribbon.x3d

PDB-4R1V-surf-bychain.x3d

PDB-4R1V-surf-hydropathy.x3d

PDB-4R1V-surf-coulombic.x3d

PDB-4R1V-surf.x3d

QR Code for https://3dprint.nih.gov/discover/3dpx-015463

Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors

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