Crystal structure of CDK4 in complex with CyclinD1 and P27

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Created on Thu, 2021-01-14 18:23, last updated on Thu, 2021-01-14 18:23

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-015363

Category

Proteins, Macromolecules and Viruses

Keyword(s)

Cyclin-dependent kinase, kinase inhibitor, CELL CYCLE, TRANSFERASE

Protein Data Bank ID

6P8E

Experimental Method

X-RAY DIFFRACTION

Resolution

2.3

Model Details

Associated Species

Spodoptera frugiperda

Oligomeric Details

trimeric

R-Factor

0.1751

Scattering Type

x-ray

Attribution

PubMed ID

31 831 640

Digital Object Identifier (DOI)

10.1126/science.aaw2106

Citation Title

p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.

Citation Year

2019

STL/VRML Files

PDB-6P8E-ribbon-secondary.wrl

PDB-6P8E-ribbon-rainbow.wrl

PDB-6P8E-ribbon-bychain.wrl

PDB-6P8E-ribbon.stl

PDB-6P8E-surf-bychain.wrl

PDB-6P8E-surf-hydropathy.wrl

PDB-6P8E-surf-coulombic.wrl

PDB-6P8E-surf.stl

PDB-6P8E.zip

X3D Files

PDB-6P8E-ribbon-secondary.x3d

PDB-6P8E-ribbon-rainbow.x3d

PDB-6P8E-ribbon-bychain.x3d

PDB-6P8E-ribbon.x3d

PDB-6P8E-surf-bychain.x3d

PDB-6P8E-surf-hydropathy.x3d

PDB-6P8E-surf-coulombic.x3d

PDB-6P8E-surf.x3d

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Crystal structure of CDK4 in complex with CyclinD1 and P27

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