Skip to main content
U.S. Department of Health and Human Services
—
National Institutes of Health
Create Account
Login
Main menu
Discover
Share
Create
Learn
Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 36
Autogenerated by
for
bejan3D
Created on Sun, 2020-05-17 22:58, last updated on Sun, 2020-05-17 22:58
I Printed This
Remix It
Vertical Tabs
General Information
This Model was autogenerated from the
"Quick Submit"
tool.
Model ID
3DPX-014367
Category
Proteins, Macromolecules and Viruses
Keyword(s)
receptor tyrosine kinase, INHIBITOR, Crizotinib, NEUROBLASTOMA, CD246, PHOSPHOTRANSFERASE, NPM-ALK, EML4-ALK, TRANSFERASE-INHIBITOR complex
Protein Data Bank ID
4FOD
Experimental Method
X-RAY DIFFRACTION
Resolution
2.00
Model Details
Associated Species
Spodoptera frugiperda
Oligomeric Details
monomeric
R-Factor
0.1796
Scattering Type
x-ray
Attribution
PubMed ID
22 734 674
Digital Object Identifier (DOI)
10.1021/jm3005866
Citation Title
The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer.
Citation Year
2012
STL/VRML Files
PDB-4FOD-ribbon-secondary.wrl
PDB-4FOD-ribbon-rainbow.wrl
PDB-4FOD-ribbon-bychain.wrl
PDB-4FOD-ribbon.stl
PDB-4FOD-surf-bychain.wrl
PDB-4FOD-surf-hydropathy.wrl
PDB-4FOD-surf-coulombic.wrl
PDB-4FOD-surf.stl
PDB-4FOD.zip
X3D Files
PDB-4FOD-ribbon-secondary.x3d
PDB-4FOD-ribbon-rainbow.x3d
PDB-4FOD-ribbon-bychain.x3d
PDB-4FOD-ribbon.x3d
PDB-4FOD-surf-bychain.x3d
PDB-4FOD-surf-hydropathy.x3d
PDB-4FOD-surf-coulombic.x3d
PDB-4FOD-surf.x3d
Rating
1
Average:
1
(
1
vote)
Licensing
Comments
0