Crystal structure of BRAF-V600E bound to GDC0879

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PTB1

Created on Sun, 2020-05-03 07:18, last updated on Mon, 2020-05-04 00:27

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-014207

Category

Proteins, Macromolecules and Viruses

Keyword(s)

RAF, MAPK, kinase domain, ATP-binding, ERK, Ras, PAK, active conformation, TRANSFERASE-TRANSFERASE INHIBITOR complex

Protein Data Bank ID

4MNF

Experimental Method

X-RAY DIFFRACTION

Resolution

2.802

Model Details

Associated Species

Trichoplusia ni

Oligomeric Details

dimeric

R-Factor

0.2146

Scattering Type

x-ray

Attribution

PubMed ID

25 155 755

Digital Object Identifier (DOI)

10.1016/j.ccr.2014.07.007

Citation Title

Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling.

Citation Year

2014

STL/VRML Files

PDB-4MNF-ribbon-secondary.wrl

PDB-4MNF-ribbon-rainbow.wrl

PDB-4MNF-ribbon-bychain.wrl

PDB-4MNF-ribbon.stl

PDB-4MNF-surf-bychain.wrl

PDB-4MNF-surf-hydropathy.wrl

PDB-4MNF-surf-coulombic.wrl

PDB-4MNF-surf.stl

PDB-4MNF.zip

X3D Files

PDB-4MNF-ribbon-secondary.x3d

PDB-4MNF-ribbon-rainbow.x3d

PDB-4MNF-ribbon-bychain.x3d

PDB-4MNF-ribbon.x3d

PDB-4MNF-surf-bychain.x3d

PDB-4MNF-surf-hydropathy.x3d

PDB-4MNF-surf-coulombic.x3d

PDB-4MNF-surf.x3d

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Crystal structure of BRAF-V600E bound to GDC0879

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