Human DNA Topoisomerase I (70 Kda) In Complex With The Indolocarbazole SA315F and Covalent Complex With A 22 Base Pair DNA Duplex

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DavidRichards97

Created on Fri, 2020-02-07 13:34, last updated on Fri, 2020-02-07 13:35

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID 

3DPX-012934

Category 

Proteins, Macromolecules and Viruses

Keyword(s) 

COMPLEX (ISOMERASE-DNA), DNA, TOPOISOMERASE I, drug, poison, ISOMERASE-DNA complex

Protein Data Bank ID 

1SEU

Experimental Method 

X-RAY DIFFRACTION

Resolution 

3

Model Details

Associated Species 

Spodoptera frugiperda

Oligomeric Details 

tetrameric

Scattering Type 

x-ray

Attribution

PubMed ID 

15 801 827

Digital Object Identifier (DOI) 

10.1021/jm049146p

Citation Title 

Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex

Citation Year 

2005

STL/VRML Files

 

PDB-1SEU-ribbon-secondary.wrl

PDB-1SEU-ribbon-rainbow.wrl

PDB-1SEU-ribbon-bychain.wrl

PDB-1SEU-ribbon.stl

PDB-1SEU-surf-bychain.wrl

PDB-1SEU-surf-hydropathy.wrl

PDB-1SEU-surf-coulombic.wrl

PDB-1SEU-surf.stl

PDB-1SEU.zip

X3D Files

 

PDB-1SEU-ribbon-secondary.x3d

PDB-1SEU-ribbon-rainbow.x3d

PDB-1SEU-ribbon-bychain.x3d

PDB-1SEU-ribbon.x3d

PDB-1SEU-surf-bychain.x3d

PDB-1SEU-surf-hydropathy.x3d

PDB-1SEU-surf-coulombic.x3d

PDB-1SEU-surf.x3d

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