U.S. Department of Health and Human Services — National Institutes of Health

Structure of Human PARP-1 bound to a DNA double strand break in complex with (2Z)-2-(2,4-dihydroxybenzylidene)-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide

Autogenerated by

for

Created on Sun, 2019-12-01 17:47, last updated on Sun, 2019-12-01 17:47

I Printed This

Remix It

Vertical Tabs

General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-012614

Category

Proteins, Macromolecules and Viruses

Protein Data Bank ID

Keyword(s)

poly(adp-ribosyl)ation

TRANSFERASE-DNA-TRANSFERASE INHIBITOR complex

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

Escherichia coli

Resolution

3.65

Oligomeric Details

tetrameric

R-Factor

0.30022

Scattering Type

x-ray

Attribution

PubMed ID

Digital Object Identifier (DOI)

10.1021/jm5002502

Discovery and Structure-Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors.

Citation Year

2014

STL/VRML Files

PDB-4OQA-ribbon-secondary.wrl

PDB-4OQA-ribbon-rainbow.wrl

PDB-4OQA-ribbon-bychain.wrl

PDB-4OQA-ribbon.stl

PDB-4OQA-surf-bychain.wrl

PDB-4OQA-surf-hydropathy.wrl

PDB-4OQA-surf-coulombic.wrl

PDB-4OQA-surf.stl

X3D Files

PDB-4OQA-ribbon-secondary.x3d

PDB-4OQA-ribbon-rainbow.x3d

PDB-4OQA-ribbon-bychain.x3d

PDB-4OQA-ribbon.x3d

PDB-4OQA-surf-bychain.x3d

PDB-4OQA-surf-hydropathy.x3d

PDB-4OQA-surf-coulombic.x3d

PDB-4OQA-surf.x3d

PDB-4OQA-ribbon-secondary.x3d

PDB-4OQA-ribbon-rainbow.x3d

PDB-4OQA-ribbon-bychain.x3d

PDB-4OQA-ribbon.x3d

PDB-4OQA-surf-bychain.x3d

PDB-4OQA-surf-hydropathy.x3d

PDB-4OQA-surf-coulombic.x3d

PDB-4OQA-surf.x3d

QR Code for https://3dprint.nih.gov/discover/3dpx-012614

Rating

No votes yet

Licensing

Comments

0