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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-012480

Category

Proteins, Macromolecules and Viruses

Keyword(s)

ACID-BETA-GLUCOSIDASE, N-NONYL-DEOXYNOJIRIMYCINALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, N-NONYL-DEOXYNOJIRIMYCIN, GAUCHER DISEASE, Disease mutation, LIPID METABOLISM, Polymorphism, glycoprotein, Pharmaceutical

Protein Data Bank ID

2V3E

Experimental Method

X-RAY DIFFRACTION

Resolution

2.00

Model Details

Associated Species

DAUCUS CAROTA

Oligomeric Details

monomeric

R-Factor

0.163

Scattering Type

x-ray

Attribution

PubMed ID

17 666 401

Digital Object Identifier (DOI)

10.1074/JBC.M705005200

Citation Title

Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid Beta-Glucosidase: Insights Into the Mechanism of Chemical Chaperone Action in Gaucher Disease.

Citation Year

2007