Ras:SOS:Ras in complex with a small molecule activator

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pkritsch

Created on Tue, 2018-11-20 14:29, last updated on Tue, 2018-11-20 14:29

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-010115

Category

Proteins, Macromolecules and Viruses

Keyword(s)

Ras, SOS, INHIBITOR, ONCOPROTEIN, PROTEIN-PROTEIN COMPLEX, MAPK, SIGNALING PROTEIN

Protein Data Bank ID

6BVJ

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

Escherichia coli

Resolution

1.747

Oligomeric Details

trimeric

R-Factor

0.1562

Scattering Type

x-ray

Attribution

PubMed ID

29 856 609

Digital Object Identifier (DOI)

10.1021/acs.jmedchem.8b00360

Citation Title

Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.

Citation Year

2018

STL/VRML Files

PDB-6BVJ-ribbon-secondary.wrl

PDB-6BVJ-ribbon-rainbow.wrl

PDB-6BVJ-ribbon-bychain.wrl

PDB-6BVJ-ribbon.stl

PDB-6BVJ-surf-bychain.wrl

PDB-6BVJ-surf-hydropathy.wrl

PDB-6BVJ-surf-coulombic.wrl

PDB-6BVJ-surf.stl

PDB-6BVJ.zip

X3D Files

PDB-6BVJ-ribbon-secondary.x3d

PDB-6BVJ-ribbon-rainbow.x3d

PDB-6BVJ-ribbon-bychain.x3d

PDB-6BVJ-ribbon.x3d

PDB-6BVJ-surf-bychain.x3d

PDB-6BVJ-surf-hydropathy.x3d

PDB-6BVJ-surf-coulombic.x3d

PDB-6BVJ-surf.x3d

QR Code for https://3dprint.nih.gov/discover/3dpx-010115

Ras:SOS:Ras in complex with a small molecule activator

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