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Ras:SOS:Ras in complex with a small molecule activator
Autogenerated by
for
pkritsch
Created on Tue, 2018-11-20 14:29, last updated on Tue, 2018-11-20 14:29
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General Information
This Model was autogenerated from the
"Quick Submit"
tool.
Model ID
3DPX-010115
Category
Proteins, Macromolecules and Viruses
Keyword(s)
Ras, SOS, INHIBITOR, ONCOPROTEIN, PROTEIN-PROTEIN COMPLEX, MAPK, SIGNALING PROTEIN
Protein Data Bank ID
6BVJ
Experimental Method
X-RAY DIFFRACTION
Resolution
1.747
Model Details
Associated Species
Escherichia coli
Oligomeric Details
trimeric
R-Factor
0.1562
Scattering Type
x-ray
Attribution
PubMed ID
29 856 609
Digital Object Identifier (DOI)
10.1021/acs.jmedchem.8b00360
Citation Title
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.
Citation Year
2018
STL/VRML Files
PDB-6BVJ-ribbon-secondary.wrl
PDB-6BVJ-ribbon-rainbow.wrl
PDB-6BVJ-ribbon-bychain.wrl
PDB-6BVJ-ribbon.stl
PDB-6BVJ-surf-bychain.wrl
PDB-6BVJ-surf-hydropathy.wrl
PDB-6BVJ-surf-coulombic.wrl
PDB-6BVJ-surf.stl
PDB-6BVJ.zip
X3D Files
PDB-6BVJ-ribbon-secondary.x3d
PDB-6BVJ-ribbon-rainbow.x3d
PDB-6BVJ-ribbon-bychain.x3d
PDB-6BVJ-ribbon.x3d
PDB-6BVJ-surf-bychain.x3d
PDB-6BVJ-surf-hydropathy.x3d
PDB-6BVJ-surf-coulombic.x3d
PDB-6BVJ-surf.x3d
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