U.S. Department of Health and Human Services — National Institutes of Health

STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN

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JacobBlumberg

Created on Tue, 2016-03-01 12:43, last updated on Tue, 2016-03-01 12:50

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-002951

Category

Proteins, Macromolecules and Viruses

Keyword(s)

HTP, CHEMOTAXIS, TRANSFERASE, Disease mutation, glycosyltransferase, ANGIOGENESIS, Growth factor, DIFFERENTIATION, DEVELOPMENTAL PROTEIN, HUMAN THYMIDINE PHOSPHORYLASE

Protein Data Bank ID

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

ESCHERICHIA COLI

Resolution

2.300

Oligomeric Details

dimeric

R-Factor

0.248

Scattering Type

x-ray

Attribution

PubMed ID

Digital Object Identifier (DOI)

10.1042/BJ20060513

Citation Title

Structural Basis for Non-Competitive Product Inhibition in Human Thymidine Phosphorylase: Implications for Drug Design.

Citation Year

2006

STL/VRML Files

PDB-2J0F-ribbon-secondary.wrl

PDB-2J0F-ribbon-rainbow.wrl

PDB-2J0F-ribbon-bychain.wrl

PDB-2J0F-ribbon.stl

PDB-2J0F-ribbon-thick.stl

PDB-2J0F-surf-bychain.wrl

PDB-2J0F-surf-hydropathy.wrl

PDB-2J0F-surf-coulombic.wrl

PDB-2J0F-surf.stl

X3D Files

PDB-2J0F-ribbon-secondary.x3d

PDB-2J0F-ribbon-rainbow.x3d

PDB-2J0F-ribbon-bychain.x3d

PDB-2J0F-ribbon.x3d

PDB-2J0F-ribbon-thick.x3d

PDB-2J0F-surf-bychain.x3d

PDB-2J0F-surf-hydropathy.x3d

PDB-2J0F-surf-coulombic.x3d

PDB-2J0F-surf.x3d

Blender Files

PDB-2J0F-ribbon-secondary.blend

PDB-2J0F-ribbon-rainbow.blend

PDB-2J0F-ribbon-bychain.blend

PDB-2J0F-ribbon.blend

PDB-2J0F-ribbon-thick.blend

PDB-2J0F-surf-bychain.blend

PDB-2J0F-surf-hydropathy.blend

PDB-2J0F-surf-coulombic.blend

PDB-2J0F-surf.blend

PDB-2J0F-ribbon-secondary.x3d

PDB-2J0F-ribbon-rainbow.x3d

PDB-2J0F-ribbon-bychain.x3d

PDB-2J0F-ribbon.x3d

PDB-2J0F-ribbon-thick.x3d

PDB-2J0F-surf-bychain.x3d

PDB-2J0F-surf-hydropathy.x3d

PDB-2J0F-surf-coulombic.x3d

PDB-2J0F-surf.x3d

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