U.S. Department of Health and Human Services — National Institutes of Health

Crystal Structure of Anaplastic Lymphoma Kinase Complexed with LDK378

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clee

Created on Thu, 2016-01-14 17:45, last updated on Thu, 2016-01-14 17:45

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-002644

Category

Proteins, Macromolecules and Viruses

Protein Data Bank ID

Keyword(s)

TRANSFERASE-TRANSFERASE INHIBITOR complex

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

Spodoptera frugiperda

Resolution

2.01

Oligomeric Details

monomeric

R-Factor

0.1734

Scattering Type

x-ray

Attribution

PubMed ID

24 675 041

Digital Object Identifier (DOI)

10.1158/2159-8290.CD-13-0846

The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer.

Citation Year

2014

Crystal Structure of Anaplastic Lymphoma Kinase Complexed with LDK378

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