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Crystal Structure of Anaplastic Lymphoma Kinase Complexed with LDK378
Autogenerated by
for
clee
Created on Thu, 2016-01-14 17:45, last updated on Thu, 2016-01-14 17:45
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General Information
This Model was autogenerated from the
"Quick Submit"
tool.
Model ID
3DPX-002644
Category
Proteins, Macromolecules and Viruses
Keyword(s)
kinase domain, PHOSPHOTRANSFERASE, ATP binding, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Protein Data Bank ID
4MKC
Experimental Method
X-RAY DIFFRACTION
Resolution
2.01
Model Details
Associated Species
Spodoptera frugiperda
Oligomeric Details
monomeric
R-Factor
0.1734
Scattering Type
x-ray
Attribution
PubMed ID
24 675 041
Digital Object Identifier (DOI)
10.1158/2159-8290.CD-13-0846
Citation Title
The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer.
Citation Year
2014
STL/VRML Files
PDB-4MKC-ribbon-secondary.wrl
PDB-4MKC-ribbon-rainbow.wrl
PDB-4MKC-ribbon-bychain.wrl
PDB-4MKC-ribbon.stl
PDB-4MKC-ribbon-thick.stl
PDB-4MKC-surf-bychain.wrl
PDB-4MKC-surf-hydropathy.wrl
PDB-4MKC-surf-coulombic.wrl
PDB-4MKC-surf.stl
PDB-4MKC.zip
X3D Files
PDB-4MKC-ribbon-secondary.x3d
PDB-4MKC-ribbon-rainbow.x3d
PDB-4MKC-ribbon-bychain.x3d
PDB-4MKC-ribbon.x3d
PDB-4MKC-ribbon-thick.x3d
PDB-4MKC-surf-bychain.x3d
PDB-4MKC-surf-hydropathy.x3d
PDB-4MKC-surf-coulombic.x3d
PDB-4MKC-surf.x3d
Blender Files
PDB-4MKC-ribbon-secondary.blend
PDB-4MKC-ribbon-rainbow.blend
PDB-4MKC-ribbon-bychain.blend
PDB-4MKC-ribbon.blend
PDB-4MKC-ribbon-thick.blend
PDB-4MKC-surf-bychain.blend
PDB-4MKC-surf-hydropathy.blend
PDB-4MKC-surf-coulombic.blend
PDB-4MKC-surf.blend
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