U.S. Department of Health and Human Services — National Institutes of Health

MULTIPLE BINDING MODES OF ANTICANCER DRUG ACTINOMYCIN D: X-RAY, MOLECULAR MODELING, AND SPECTROSCOPIC STUDIES OF D(GAAGCTTC)2-ACTINOMYCIN D COMPLEXES AND ITS HOST DNA

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Created on Thu, 2015-03-05 21:37, last updated on Tue, 2022-05-17 14:41

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-001131

Category

Proteins, Macromolecules and Viruses

Keyword(s)

ACTINOMYCIN, ANTIBIOTIC, ANTITUMOR, ANTICANCER, Chromophore, DEPSIPEPTIDE, DNA-ANTIBIOTIC COMPLEX

Protein Data Bank ID

173D

Experimental Method

X-RAY DIFFRACTION

Resolution

3.000

Model Details

Oligomeric Details

tetrameric

R-Factor

0.202

Scattering Type

x-ray

Attribution

Digital Object Identifier (DOI)

10.1021/JA00089A002

Citation Title

Multiple Binding Modes of Anticancer Drug Actinomycin D: X-Ray, Molecular Modeling, and Spectroscopic Studies of D(Gaagcttc)2-Actinomycin D Complexes and its Host DNA

Citation Year

1994

MULTIPLE BINDING MODES OF ANTICANCER DRUG ACTINOMYCIN D: X-RAY, MOLECULAR MODELING, AND SPECTROSCOPIC STUDIES OF D(GAAGCTTC)2-ACTINOMYCIN D COMPLEXES AND ITS HOST DNA

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