U.S. Department of Health and Human Services — National Institutes of Health

Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122

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Created on Fri, 2015-01-16 23:01, last updated on Thu, 2017-03-30 15:05

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General Information

This Model was autogenerated from the "Quick Submit" tool.

Model ID

3DPX-000969

Category

Proteins, Macromolecules and Viruses

Keyword(s)

Type-1 membrane fusion glycoprotein trimer, HIV-1 envelope, gp120, gp41, membrane fusion, viral entry, CD4, CCR5/CXCR4, broadly neutralizing antibodies, viral surface

Protein Data Bank ID

4NCO

Model Details

Experimental Method

X-RAY DIFFRACTION

Associated Species

Homo sapiens

Resolution

4.7

Oligomeric Details

dodecameric

R-Factor

0.3759

Scattering Type

x-ray

Attribution

PubMed ID

24 179 159

Digital Object Identifier (DOI)

10.1126/science.1245625

Citation Title

Crystal structure of a soluble cleaved HIV-1 envelope trimer.

Citation Year

2013

Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122

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